...I don't think there's anything spoilerish here.

All of the sudden my companion won't talk to me. He just moves back quickly. I've checked and I don't have any diseases and I'm not poisoned. And generally I couldn't shut him up if I was close, but now there's a big nothing. The only think I can think of is I made him wait and I got a popup about him being tired of waiting and...went somewhere else.

Anyone got any ideas on this?