A good way to sum up House vs. Indy is to bring Arcade Gannon with you when you go to talk to Thomas Hildern at Camp McCarren. Hear Hildern out and exhaust his dialog options, then talk to Arcade.
Arcade basically represents Indy whereas Hildern represents House. Hildern is willing to sacrifice bodies for the greater good and views it as "4 lives to improve the life of 4000," whereas Arcade believes each life is special and you can't really look at humans as statistics.
House really is the best option for Vegas of the existing nations, as he's got the most solid, flawless plan to move forward. No one doubts his security, his genius and his ability to address and solve potential issues. However, House will undoubtedly walk over people, typically "the little guy." Freeside, for example, may not benefit from House. Westside is another one, as are Sarah Weintraub and Michael Angelo. House creates a nation where progress is the focus, the problem being that when two people have conflicting interests, the more powerful and influencial person (the one who brings about more progress) will always get their way. Indy on the other hand promises EVERYONE a chance (save the people you personally get rid of) but at the cost of everyone being in the same boat, i.e., everyone is suddenly at risk of any potential problems that may come about. One's a thinker, the other's a dreamer.
In that sense, although many people initially interpret Indy as the selfish decision, it actually has less to do with selfish gain and more to do with the belief and ideology that everyone deserves a chance. Under House, 50% of the population is VERY secure and 50% is in an incredibly unstable living. Think of Indy as....Indy compromises the top 50% down and the bottom 50% up, so everyone's kinda on par, but of course living standards for the top 50% have taken a massive hit. The BEST living standard isn't nearly as good as it used to be, but at least the WORST living standard has significantly improved. Again, think of it like House has the greater
potential for
some people, but Indy provides an
adequate living standard to
more people.
For that reason, I'd pick House. If he's selfish and isn't afraid to kill innocent people, House offers a greater POTENTIAL standard of living than Indy, and as House's agent, you're obviously first in line to get the best-of-the-best.