(mana regeneration slow/fast , all creatures hostile yes/no , overpowered Daedric artifacts yes/no (think skeleton key or azura star) , and so on .....)
And there is a group of people who want it one way and a group which wants it the other way.
(with endless bickering in between)
The problem arises because most of there groups have valid arguments and only one will end up getting what they want.
But there is a simple way to make most people happy , just add a setting panel next to difficulty slider with a few dozen of the most asked for tweaks.
This way everybody can adjust or turn on/off things as they like.
Some will say we have mods for that but mods are problematic.
Console players don't get to have them ( muhahahahahaha ) , and PC folk have to tolerate bugs, messy instantiations and and whole bunch of other problems.
Having Bethesda do this this themselves would be appreciated.