Well, you could dump your stuff on the ground/in a container and fast travel with your item weight lowered, then take some items back and vice-verca...
I'm weird. I won't fast-travel because it makes no sense. But I'll walk home with an insane amount of stuff (after I've gotten past the encumbrance limit with my list of "must takes"....new weapons and valuable resources....I figure I might as well take everything I come acrosss), in this case I hit 3001 units by the time I got back to Megaton. Game really needs a weight where you can't move at all.
More on point, on the way home I was slowly approaching a dead raider to take his loot and just before I got into activation range he faded away before my eyes.