Obviously some parts were scripted for the E3 demo but there were some things I noticed that were different to the finished game:
Coloured reticle
Map
Voice actors
And the part where Todd said "there are over 200 hand crafted dungeons." I believe that's what they intended but found it was way too much work. Don't worry I'm sure the 150 dungeons in Skyrim will be hand crafted, they have a much bigger team now.