The reason I ask is because I'm about to create a brand new character who is going to ally with House and follow all his main quests to the ending. I like to write and roleplay a history for each of my characters, and this particular one will believe in House's ideals to the point where they want to see the NCR and Legion weakened enough so that House can continue to rule the Mojave uncontested. However, if nuking both the factions would actually get House's disapproval (much like he actually doesn't want the Courier to kill Caesar), they wouldn't do it.
Yes, I'm aware that House doesn't actually acknowledge the Courier's actions at all outside of the Lonesome Road DLC. Let's just pretend for a moment that he actually does.