Just a note, to the crowd who think VATS is a waste or a crutch ... You DO realize this is an RPG, right? Not an FPS. We have skill points that govern our characters abilities, instead of relying on our own abilities.
Do you disable dialog from displaying [Speech %] when a speech check is available? Do you only carry as much weight as you personally could carry? Do you repair and build weapons in game, that you could never figure out IRL?
You let the stats for your character dictate these skills. Why not let your character stats dictate you skill with guns (or energy weapons, melee, etc.) Using VATS us no different than rolling a d20 and checking vs THAC0. And bonus points to whoever gets that reference w/o googling.
Oh ... All that said, I use it for combat primarily. Feels like it's intended use (per my long winded bs above) so that's how I use it most often.