I little thing i've noticed this time around, many of the interiors are much larger or more oddly shaped than the building it represents. Bethesda has done, through Morrowind, Oblivion and Fallout 3, exceptionally well with matching the size of an interior with the building in the game world.

Fallout New Vegas has some pretty obvious inconsistencies, such as a guard shack over the railroad track that is a little larger than an in-game car outside, but some 10x larger inside. The cabins in Jacobstown are the same way, along with many of the houses and shacks throughout the wasteland.

Not in any way a game breaker, just a small "whoah, that was trippy" glitch. I guess the man who invented the huuge pockets that come with your standard Pipboy grew up in the greater New Vegas area.