With the recent fix my initial load times are back to normal with the Beta patch however I'm noticing that when transitioning from interior to exterior cells the load times are still significantly longer than they were previous to this patch.

I just did a brief test with and without the beta patch loaded. My initial game load I was inside the Corvega Factory and it loaded within 5-10 seconds. Exiting the factory into the Commonwealth took around the same time. I ran around the outside of the building and entered the factory via another door and the load time took upward of 30 seconds. Without the Beta patch that last load back into the factory was reduced to around 10 seconds.

Now I realize that this is not as substantial an increase as the previous issues but without the beta patch it was loading much quicker. Has anyone else noticed this? As a side note: I am running a few mods and have not tested the load times without them. I have also verified game integrity and all files were good.

Yeah, I have noticed the same thing. I have a couple mods installed but nothing major, just a couple of textures replaced and some UI tweaks. Only one has an .esp. The weird thing is that sometimes I've been stuck on what seems to be an infinite load screen, but as soon as I open the Windows task manager to shut off the game assuming it had just crashed the game immediately finishes loading.

Yes I had this just last night! Granted I couldn't get back into the game after and I had to restart my system to get the game to load again...