With this guide you should be able to avoid some common problems like CTDs, texture issues and crashes on start up. Also shows how to create a merged patch, setting up your load order etc...
http://www.youtube.com/watch?v=n_ix-dOGfXs: Fallout installation, Multicore fix, FOSE, Fallout Mod Manager, mod downloads...
http://www.youtube.com/watch?v=FDWzcb01Xug: Mod downloads, mod installation via FOMM
http://www.youtube.com/watch?v=ueEh38BUP2w: Mod installation via FOMM, archive invalidation, setting up your load order
http://www.youtube.com/watch?v=wMhUR9rpatA: Creating a Merged Patch and finalizing load order
Tools used:
http://www.7-zip.org/
http://fose.silverlock.org/
http://fallout3nexus.com/downloads/file.php?id=1086
http://fallout3nexus.com/downloads/file.php?id=640
http://fallout3nexus.com/downloads/file.php?id=637
Mods demonstrated:
http://fallout3nexus.com/downloads/file.php?id=2761
http://ui.darnified.net/wip/F3/dui_f3a11.zip
http://fallout3nexus.com/downloads/file.php?id=3211
http://fallout3nexus.com/downloads/file.php?id=3388
http://fallout3nexus.com/downloads/file.php?id=8340
http://fallout3nexus.com/downloads/file.php?id=6341
http://fallout3nexus.com/downloads/file.php?id=4968
If this video was helpful to you and you would like to raise awareness for it, please download the small zip file in the downloads section to endorse this video on http://fallout3nexus.com/downloads/file.php?id=13111.