WARNING: I am quite certain that there is at least one HUGE spoiler at the end of this post.
In a http://www.gamesas.com/topic/1523944-replay-value/?p=24156836, I suggested that the names of our respective male and female protagonists will actually be Jack and Nora. Here's what I said:
Slightly unrelated but interesting nonetheless:
We already know that if we select a male protagonist, his spouse is called "Nora". We also know that our son is called "Shaun". I'm wondering that maybe if we choose to play as a female, her husband will be called "Jack".
There are several reasons why this may be the case. Firstly, all 3 names are believed to have an Irish origin, which would fit perfectly with the historical Boston setting. Secondly, both Shaun and Jack actually have the same derived meaning, which is "God is gracious". Note that Nora actually has 2 derived meanings, which are "light" (as in lighthouse) and "honor".
Finally, if we put the two potential protagonists' names together, we get JackandNora, or Jackanory. Given the obvious British connection of the Revolutionary War, it is interesting that this word literally means story.
EDIT: re replay value. Suddenly, I want to play Fallout 4 at least twice just to find out!
As I had suggested, I believe that the default names for our male and female protagonists will be Jack and Nora (as in Jackanory). I have already explained a number of reasons why I believe this to be the case in the post shown above. But now let's consider the actual https://en.wikipedia.org/wiki/Jackanory of the word 'Jackanory'. Here is the nursery rhyme published around 1760 from which the word is derived:
I'll tell you a story
About Jack a Nory;
And now my story's begun;
I'll tell you another
Of Jack and his brother,
And now my story is done.
What's actually really interesting about this is the fact that, if Shaun was taken out of the vault before the protagonist (assuming we have selected a male character), he would likely be old enough to be mistaken as being his brother rather than his son. And so the premise of the story actually fits perfectly with the wording of the nursery rhyme.
But, if that isn't enough to convince you, let's look at a few additional facts. Firstly, as I stated above, the names Jack and Shaun are both derived from the same source, just as both of their respective characters are similarly connected in-game (as per their DNA, along with that of Shaun's mother). Secondly, the use of a nursery rhyme as the source of both of the parents names is more than fitting considering the inclusion of a baby, as well as the previous use of the "SPECIAL" book in Fallout 3. Third, the date of the original publication of this nursery rhyme is startlingly close to the beginning of the revolutionary war, which as we already know, is very closely linked to Fallout 4's story.
But the final point is the one that interests me the most. The nursery rhyme shown above actually tells of two stories, one involving 'Jack a Nory', as in Jack and Nora. And the second involving Jack and his brother, which seems very much like a reference to Jack and Shaun, as detailed above. What this suggests is that the first part of the game, as in the pre-war tutorial, is the story of our couple, who have just started a family together, but are tragically and unexpectedly caught up in a nuclear war that almost wipes us out of existence.
As for the second part of the story, it would seem that the post-war portion of gameplay will be focused around two individuals, or two opposing sides from the same source. And so it is my belief, as I have hinted at in other threads, that the culmination of the main quest will be a very personal battle between our protagonist and their son.
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EDIT: another story that fits perfectly with what we know of Fallout 4 is Rip Van Winkle (as seen https://en.wikipedia.org/wiki/Rip_Van_Winkle). This was suggested by Dinrauko, and as such I have quoted part of their post below:
"In the story of Rip Van Winkle, Rip falls asleep before the Revolutionary War and awakens 20 years later to find his world has changed. His dog is gone, his wife is deceased, and his children have grown up. People he used to know have gone away or died in the war. The Wikipedia article describes Rip Van Winkle's son as a never-do-well, which fits with the OP's prediction that the protagonist's son is the antagonist."