I wholeheartedly believe that Bethesda can do better in the development of professions, such as becoming a blacksmith, in comparison to games that have done it before such as Fable. The idea of becoming a blacksmith (I'll just use blacksmith as my profession example) and owning/running your own business, even helping run an existing business, is just an option that should always be available, even to people who only care to dungeon delve and murder the crap out of every daedra in sight. "Open world RPG"s are, in my opinion, being limited nowadays. They are being simplified down for anyone to come in and play with ease. Now I don't mean to say make the game seem ridiculously impossible to survive at first like Morrowind (for some), but instead the game should play out through a simple and moderately detailed tutorial that covers the near obvious aspects of the game, but leaves lingering hints as to what further research into those aspects could lead to.
Professions could be listed just like skills, with their own levels, skill perks (Taking from Oblivion, the perks gained at 25, 50, 75, and 100), and world interaction benefits just for being at a certain level in a profession. They wouldn't raise your overall level because they aren't your character skills, they are your character professions. On a side note, they should de-categorize weapon skills in my opinion. It was annoying to think that a barbarian who only ever knew how to wield big weapons like claymores and warhammers, could use a dagger just as good because his Blade skill had been increased by use of the claymore. No. That's just silly. In my opinion they should really detail it down to skills like, Daggers, Broadswords, Katanas, Longswords, Tantos, Wakazashis, etc etc. Just a thought.
Owning your own shop should be difficult in my opinion. You shouldn't be able to be some scruffy half-orc with a taste for blood and expect smiling customers in a shop you managed to open using the money you gained from slaughtering the city to your west. It should be an ultimate test of the speechcraft and mercantile skills, supported by your professions. You could add in a profession of entrepreneur just to make the possibility of owning every shop a rogue's dream come true.
Just thinkin.
Eureka! The only exception I would add, is I don't think skills and weapon specialties, and professions should all be listed... At first... We should be made aware of 'obvious' skills in our menu up front, but certain professions, exotic weapon skills, and specific specialties, should only be added after we discover them, both to cut down on clutter, as well as add to immersion, and emphasize the fact that these things are OPTIONAL.