Tips:
- Proceed with caution. There game is very hard in the start, but it will get ridiculously easy after you get the hold of it.
- Speak to all people you see. Especially named ones. There are plenty of quests in the game.
- Don't take too many chems at lower levels. Addictions are a real pain in the ass in this game.
- Stay away from the mid-coastal area until you are directed there. The Enclave doesn't like visitors.
- Remember to patch your game, and even better, get Killap's Fallout 2 Restoration Project from NMA.
- Power armor will make you pretty much invincible against conventional weaponry.
- Critical hits hurt. Usually, at later levels with Power Armor, you may take 15 hits of no damage and then die of a single critical hit.
- Big Guns are pretty useless in this game. By the time you start getting them, you'll have Gauss Rifle which will deal with anyone.
Good starting strategy, copied from Fallout 2 walkthrough:
Team gunfighter: A bright and sociable character who can bring three friends along. You can take on all quests and pack some punch.
* Initial stats: ST 5, PE 6, EN 4, CH 6, IN 7, AG 7, LK 6.
* Developed stats: ST 10, PE 7, EN 4, CH 6, IN 8, AG 8, LK 8.
* Traits: Small Frame, Fast Shot.
* Tag skills: Small Guns, Lockpick, Speech.
* Perk progression: Level 3 Awareness, level 6 Quick Pockets, level 9 Better Criticals, level 12 Living Anatomy, level 15 Bonus Rate of Fire, level 18 Gain Agility, level 21 Action Boy, level 24 Sniper.
* Comments: Pick up Sulik, Vic and Cassidy for a posse of gunslingers. Later in the game you can switch to Big Guns (goes well with Fast Shot), perhaps in conjunction with pulse and/or gauss weapons. You need a Jet or Mentats for Sniper. Whether you should pick Living Anatomy or go for more AP is situational.