With the latest patch certain keys gained new functions, like the Activate key being the loot button too, which is super handy.
It did cause a new problem for me, though. Since we can now bind to keypad numbers, which were previously quick slots, the quick slots now appear to be tied only to the horizontal row of number keys located above the letters. That causes a problem for me since I'm a lefty and I actually used the keypad numbers for quick slots before, but now they no longer work and I have to reach for the other number keys, which makes them not quick at all.
How do I get my keypad quick slot function back?
Edit: I should add that re-adding my weapons as favorites won't allow me to use the keypad numbers either. Nothing happens when I press those.