I play with QWES for movement, A special, D interact/use.
I can mostly work with the stupid hardcoded bindings except for two places: moving around in areas crowded with containers/bodies, and the construction system.
Picking up stuff in the open works with D... but wants me to use E with containers. Strafing right while passing by a container? You stop strafing right. A body? You pick up and drag the body, slowing you down and giving you a meat shield you can't shoot through. Putting that body down again? D key.
In the construction system, Q and E are hardbound. I'm not sure what Q does, but E selects an item in the build UI (or in the world), so I can't strafe there either.
I'd go back to defaults but I am so, SO used to QWES that I would regularly find myself getting frustrated when an attempt to strafe didn't work... because I was hitting the wrong key. Nevermind that I don't find WASD comfortable for prolonged use.
Feedback submitted. I'm still playing but I'd really love to have this crap fixed. (I'd much rather it worked right on launch.)