- Dirge: If I hear his "even if you are one of us..." line again I'll go postal on the whole thief guild. Found it annoying that even after I became Guild Master he simply kept talking to me like that.
- Maven Black-Briar: Her snobbery and attitude got under my skin quite fast and even after she became Jarl (thanks to me no less) and after doing so many quests for her and favors she will still tell me "out of my way" or something like that.
- Priest of Talos in Whitrun: You know who he is, screaming like a fanatic in the marketplace.
I killed the priest of Talos with my first character (and will kill him again with my new character) but didn't kill Dirge or Maven. With my new character the first thing I'll do as soon as I set foot in Riften is kill Dirge and Maven. Skyrim will be a much better place without them. I think I'll just cast Frenzy on both and sit back, drink some wine and enjoy the show as everyone around them beats them to death.
Anyway, I am sure there are other NPCs I find annoying but those threes are the ones that stand out the most for me.
What about you? Any NPCs you find very annoying and who you have killed or plan to kill?