Thremic Land and Chainsaw works well, they can't get close. Using Displacer glove correctly can destroy them without taking a hit.

But nothing beat Laser RCW+Meltdown.

I find running away to be a very effective tactic.

Actually I never had any problem with Cazadors before the patch. It seems like the poison never affected me. I always got the "ur feeling a little wuzzy" message but nothing ever happened. Then after the patch I fought Cazadors several times. Each time after the fight I died for no reason I thought. There was no one attacking me. So after the third fight I took a look at my condition then it told me I was poisoned. So I took some antivenom. I was begining to wonder what it was for anyway. I almost completed the game without using it once.

I thought oh look the patch brought me a new present and then I took a look at the boards and I found out this should have been happening to me since the begining of the game. I had only one thought "This svcks",

LOL!! That is too funny.

Also...This Machine (which you can get by lvl 12 I think it is?) has always worked great for me, even without any companions to back me up. I just keep on firing while backpedaling. I almost find such enemies easier when not using VATS because VATS seems to cheat in my game where the enemy gets to advance a bit while you're still stuck in the slo-mo view, so they can reach you long before you can fire many shots. Whereas only backpedaling you can fire a lot more rounds while keeping distance.

But yeah, because of their poison, if they do hit, it can be a doozy.

10mm submachine gun and combat armor. Best advice for anyone below level 15. Other than that, get 100 lockpick quick and get the Gobi Desert Snipe Rifle.

Since the last patch (I'm on PS3), there is something new is happening. Or maybe its always been there, but I've never noticed it. :shrug:

Cazadors are poisoning my companion, Veronica. After ending the battle, she will have full health, which will rapidly decrease. Its costing me a fortune in stimpacks just keeping her alive. I've tried giving her antivenom but she won't use it.

Is this supposed to happen? :huh:

If your not on hardcoe mode just let her die or get knock out . Thats what I did for lily earlier. After she came back to, her health stop draining.

I deal with Cazadores by using either a Laser RCW or Gatling Laser loaded with MC ECP rounds in free-fire mode, and they drop almost instantly. That's without Meltdown, too.

I've also tried the Grenade Machine Gun with HE rounds, which works well with high skill. A Missile Launcher with HE rounds also works.

Really any AoE or automatic weapon will tear them up in short order, but bring 1-2 Antivenom just in case.

This might sound crazy, but a fully upgraded laser rifle with MC ammo post-patch obliterates these things once you get laser commander. I can kill entire swarms of these things outside of vats with it. Laser Rifle is beast now as long as you're crit heavy.

I used to be puzzled that people had such a hard time with Cazadores ... because my main weapon was a 9mm SMG (before I figured out how DAM and DT worked). Then I started carrying around higher DAM weapons and realized that they don't make much of a difference against these buggers unless they shoot FAST.

Try not to let Cass, Lily, Rex or Arcade fight them with you because we will usually die anyway. Boone + ED-E II is the best combo to take any enemies after the new patch from my recent experience.

Hm...personally, I've found Ed-E and a sniper rifle work quite effectively. If you have the distance. Otherwise the 5mm machine gun (the name just dashed out my head), is pretty nifty too, in close quarters. Still working up the guts to brave that mine with the legendary cazador though...*le sigh*

This. The flamer makes short work of any low DT critter.

9mm smg fully modded with fast shot and rapid reload, 10mm modded with JHP and the same perks and others will take any unarmoured foe in seconds.
The 9mm can unload its high ammo count can in around 6 secs, same for the 10mm, failing that a hunting shotgun modded with magnum shells also will do the trick.

A grenade rifle / launcher will cripple multipules leaving you to take them down at your on pace.

Ballistic Fist. This has been my favorite weapon so far against everything.

this is what I use, or riot shotgun when they get too close.

No luck,I'm afraid...I'm on hardcoe. Just got caught by a swarm of 7 of them and Veronica was suffering long after they had been killed. Whether its intentional or not, its costing a fortune in stimpacks.

Yup! My only other suggestion is to vats and Target their wings so they can't fly

use any weapon with a high rate of fire and hipfire at them , this will usually cripple the wings and they will just lie on the floor and let you laugh at them.
vats at the wings works on small groups but if there are more than 2 just pop some psycho and hipfire like a maniac

I've just taken out two swarms of approximately twenty Cazadors total (by the Brewer's Beer Bootlegging) and discovered a rather effective tactic.

Crew: You (silenced Varmint or Sniper rifle, automatic weapon for emergency backup); Ranged Companion; Melee Companion.

Tactic:

1) Find a firing position at the outer limits of VATS detection of your target. The more distance you can get, the better. Try to have a clear firing line, preferably a narrow opening in the cliffs that would canolize the Cazadores so that they would come at you from a single direction.

2) Make sure that your companions stand BEHIND you- preferably a good distance- and are both set to passive; one must be melee, one ranged. The DAM rating of the weapon of the melee companion is the second most important detail of the setup after the silencer on your own weapon; you want them to take out any Cazadore with one blow

3) VATS-snipe from Sneak mode (with a silenced weapon) at whichever Cazador exposes itself; target whichever part gives you best chance to hit, preferably wings. Reload after each unsuccessful shot that neither neutralized nor alerted any Cazadors.

4) If you hit and kill or wing-cripple a Cazador, great. If you would or simply alert the Cazador, only it and perhaps a couple of Cazadores closest to it will be alerted.

5) As the alerted Cazadores comes at you, you will have the time for several VATS-shots at them, with ever-increasing chances to hit. The greater the distance, the more shots you'll be able to fire. I would advise taking a chem that increases your action points (Rocket, Jet, etc.). Your ranged companion will start firing at the Cazadores as soon as they are in range, while your melee companion should engage and either kill or at the very least delay any Cazadore who makes it through your killing field alive.

6) After each successful skirmish, make sure no more Cazadores are coming at you, save and reposition your followers to be some distance behind you.

It takes some patience, but it works.

My last encounter with Cazadors was at the Tribal Village where about 6-7 of them were just hanging out after apparently taking out a camp/conflict of Khans and Fiends.

I died numerous times - as did Cass - until I started using my Thump Thump to hit them as soon as I could get a decent, distant shot on them (frenzied a couple of them which helped me not get completly overrun by them too quick).. then finish the last 3 or so off with my Trail Carbine.

I managed to not even get stung/poisoned by any of them with that strategy. mwahahahaha

Just make sure whenever going around territroy with cazadors carry antivenom. That is the main thing, the poison ignores dt and what cause most damage. If you use energy weapons use incinerator or flamer, they have low DT and the flaes damage over time. If guns a good scoped weapon with HP rounds and a shotgun if they gtet close (or lucky lucky is amazing).
Melee guys use shishkebab and unarmed love and hate (good weapon), but carry a hell of a lot medicine because you will get stung, alot...

Multiplas rifle is my favourite weapon for them at the moment.

Boone's serial fainting after a fight is annoying but worth it for the caps.

Oh, and if you fight them down at Callville Bay, try backing away into the water, it has an interesting effect on them.

Automatic weapon and stack +20+ heal does fine, anti-venom recommended when face rather large herd (4+).

Best tactic is to fire from really steep slope which the AI just thought they can fly over.......

i feel into a sawrn of those little buggers for the first time today (just got this game yesterday) Rex took out some of them until he got knocked out so i started laying into them with my M4.