I beat the game too, and have over 200 hours into my character as well and my file size is 13.4.
I do have older saves before I beat the game but are way earlier saves that are 10.49
No there is no problem if the save file exceeds the 10.49 barrier!
Look at topic: http://www.gamesas.com/topic/1585934-help-getting-error-code-ce-34878-0/page-2
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