Are there any problems with the major overhaul mods, midas magic, any changes to world-spaces (i run home-made mods so i need to know this) any known conflicts or changes that could happen with any other mods?
Only known problems are mentioned in the readme, which fortunately isn't a lot.
Only thing that comes to my mind at the moment is a certain Tiefling race, which wasn't used that often to begin with (if I recall correctly it supports only the BAB body).
I use FCOM, Unique Lanscapes and around a hundred of other mods myself, so I'm making sure they're compatible

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Only important thing is to load LAME after e.g. OOO.esp, otherwise you'd still get OOO's magic system mostly

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Close your eyes, folks! They are going to do it!

I just don't know when :cold:. Was ill the last couple of days, and now my already busy schedule exploded. Integration update takes priority, LAME comes next.
Does LAME remove some effects from spellmaking?
Yes, it does.
Drain Health 150 for 1 sec on target sounds like fun, but ...
Also, it seems paralysis 3 (Ita Rienus) sec is now an expert level spell?
Too powerful as a journeyman spell

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Hm. Interesting. Sounds a bit like a problem with the storage you used (e.g. if you use some kinds of clutter remover, and the area/container is unowned instead of player owned, they may get cleared despite being set to not respawn). Just a wild guess here, because the spell notes are just your typical books, with only special ability is to teach you something and setting their value to 1.