I'd prefer a little more realism than OB's drifting and fading blood decals (persistent wound marks would be an improvement), but nowhere near what was in FO3.
The problem with persistent wounds is RPG leveling.
Should my sword slash leave a wound if I'm level 1 and my opponent is level 30? It will take me
100 more slashes to kill this guy, and if every slash leaves a realistic wound, he's going to look
really ridiculous halfway through the fight....
I could leave 30 gaping slash wounds on an enemy's face and according to his stats, he would barely be hurt, etc.
Realistic, persistent wounds don't make sense in a world where RPG leveling exists. You either (A) toss stats out the window and forget about TES being an RPG or [B] just deal with severe wounds only appearing during finishing moves.