Coincidentally I'm currently experiencing ever increasingly frequently crashes on my game, so as soon as 5 minutes after loading up the game. It's also worth not that my game has be lagging slightly more than usual today. I've run a CCleaner already and removes about 200 MB, and my disk fragmentation is low. The only thing I can think of to affect my performance is that I haven't dusted me computer for a few months. However I don't think this would bring on this issue so suddenly. (It's only started today) The crashes them selves happen under no particular circumstance that I can identify.
EDIT: Scratch that, now it's happening in as little as 30 seconds. I can't play at all. I've try go to older save and see if this still persists, that might narrow it down.
Here's my load order:
[X] Fallout3.esm
[X] Anchorage.esm
[X] ThePitt.esm
[X] BrokenSteel.esm
[X] PointLookout.esm
[X] Zeta.esm
[X] Unofficial Fallout 3 Patch.esm
[X] CRAFT.esm
[X] CALIBR.esm
[X] FOOK2 - Main.esm
[X] FOOK2 - [[censored]] World And Neighbourhood Kit.esm
[X] FOOK2 - [DIK] DLC Improvement Kit.esm
[X] FO3 Wanderers Edition - Main File.esm
[X] Mart's Mutant Mod.esm
[X] Destruction.esm
[X] DCInteriors_ComboEdition.esm
[X] VATSPerkWorkaround.esm
[X] Sharing and Caring Companions.esm
[X] CMF-Zeta.esm
[X] Unofficial Fallout 3 Patch - Operation Anchorage.esp
[X] Unofficial Fallout 3 Patch - The Pitt.esp
[X] Unofficial Fallout 3 Patch - Broken Steel.esp
[X] Unofficial Fallout 3 Patch - Point Lookout.esp
[X] Unofficial Fallout 3 Patch - Mothership Zeta.esp
[X] CASM.esp
[X] CRAFT - Activation Perk.esp
[X] DarNifiedUIF3.esp
[X] GalaxyNewsRadio20[M].esp
[X] FOOK2 - Main.esp
[X] FOOK2 - [DIK] DLC Improvement Kit.esp
[X] FOOK2 - Mothership Zeta.esp
[X] FOOK2 - [DESTRUCTION] Main.esp
[X] FOOK2 - [DESTRUCTION] Main - Statics.esp
[X] FOOK2 - [DESTRUCTION] DIK.esp
[X] FOOK2 - [DESTRUCTION] DIK - Statics.esp
[X] FOOK2 - [DESTRUCTION] Mothership Zeta.esp
[X] FOOK2 - [DESTRUCTION] Mothership Zeta - Statics.esp
[X] FO3 Wanderers Edition - Main File.esp
[X] FO3 Wanderers Edition - DLC Anchorage.esp
[X] FO3 Wanderers Edition - DLC Broken Steel.esp
[X] FO3 Wanderers Edition - DLC Mothership Zeta.esp
[X] FO3 Wanderers Edition - DLC Point Lookout.esp
[X] FO3 Wanderers Edition - DLC The Pitt.esp
[X] FO3 Wanderers Edition - UFP Support.esp
[X] Tailor Maid.esp
[X] Tailor Maid Anchorage.esp
[X] Tailor Maid PITT.esp
[X] Tailor Maid Brokensteel.esp
[X] Tailor Maid ZETA.esp
[X] WeaponModKits.esp
[X] WeaponModKits - FWE Master Release.esp
[X] WeaponModKits - OperationAnchorage.esp
[X] WeaponModKits - ThePitt.esp
[X] WeaponModKits - BrokenSteel.esp
[X] WeaponModKits - PointLookout.esp
[X] WeaponModKits - Zeta.esp
[X] WeaponModKits - FOOK.esp
[X] WeaponModKits - FWE Optional Worn Weapons.esp
[X] UPP - Pack 1.esp
[X] UPP - Pack 2.esp
[X] Mart's Mutant Mod.esp
[X] Mart's Mutant Mod - DLC Anchorage.esp
[X] Mart's Mutant Mod - DLC The Pitt.esp
[X] Mart's Mutant Mod - DLC Broken Steel.esp
[X] Mart's Mutant Mod - DLC Point Lookout.esp
[X] Mart's Mutant Mod - DLC Zeta.esp
[X] Mart's Mutant Mod - No Corpse Flies.esp
[X] Mart's Mutant Mod - Feral Ghoul Rampage.esp
[X] Mart's Mutant Mod - Hunting & Looting.esp
[X] Mart's Mutant Mod - Increased Spawns.esp
[X] Mart's Mutant Mod - Natural Selection.esp
[X] Mart's Mutant Mod - Tougher Traders.esp
[X] Mart's Mutant Mod - Zones Respawn.esp
[X] Mart's Mutant Mod - FOOK2.esp
[X] Mart's Mutant Mod - FOOK2 - DIK.esp
[X] 1PipboyPDA.esp
[X] FO3 Wanderers Edition - FOOK Support.esp
[X] FWE - FOOK DLC Support.esp
[X] Mart's Mutant Mod - FWE Master Release.esp
[X] FOOK Ammo fix.esp
[X] CMF-Zeta.esp
[X] Alien Aroxy.esp
[X] WillpowerMod - FWE.esp
[X] Mart's Mutant Mod - XFO.esp
[X] PowerArmorGloves-None.esp
[X] Perk Up!.esp
[X] FO3 Wanderers Edition - More Gore.esp
[X] FLAK.esp
[X] RI_Sleep2.esp
[X] AoT_Mask.esp
[X] Unlimited Death Reload Time.esp
[X] Chad.esp
[X] RemoteControlCompanionsPlus.esp
[X] RCCP_Patch_for_SCC.esp
[X] NomNom.esp
[X] SlurpSlurp.esp
[X] XFO_SP_Fix2_(SP10_TAGx2_INTxHalf).esp
[X] Smurf_Impact_Accuracy_Skill_50percent.esp
[X] Smurf_Impact_Accuracy_Condition_60percent.esp
[X] Smurf_Impact_WpnSkillDmg_10percent.esp
[X] Smurf_Impact_Accuracy_Running.esp
[X] Smurf_Impact_Accuracy_Crouching.esp
[X] ZoomReworked.esp
[X] ImmersiveHealth.esp
[X] DefaultBulletCamHighChance.esp
[X] VATS - MCE.esp
[X] VatsLongerDistance.esp
[X] HelmPOV.esp
[X] Selective Fire.esp
[X] The Groovatron.esp
[X] The Groovatron_DLC_Anch_Addon.esp
[X] The Groovatron_DLC_Pitt_Addon.esp
[X] The Groovatron_DLC_PL_Addon.esp
[X] AutoPatch.esp