Tricky question. There are some places that are heavily modded and should be avoided, and some that places that get neglected... but it can still be difficult to find a decent location.
The best way is to know which mods are the most popular, and how to avoid conflicting with them.
But at the same time, you should focus on making your mod exactly how you wish it, and as long as your mod is clean, people can't really complain.
For a Mage home, you might want to locate it near Sadrith Mora, or one of the Mage Guilds (depending on which type of magic user you are thinking of.)
Then make sure it doesn't immediately conflict with major mods that already touch that area. But otherwise, let your imagination run free.
Also, magical homes can easily exist outside of the usual world/realm, and will therefore not really conflict with anything