So I wound up the musket and killed them at LONG range. It really saved me but I expended all my cells. It's a good thing -- they went to a good cause and I'm going to Diamond City next so I can use those caps I've been building up for some new cells but it was sure a surprise. Somehow my brain equated single shot weapon with low ammunition use.
I will say that when it's modded up, the laser musket can deliver a LOT of damage to a target at very long range very accurately. It's a great sniper rifle if you have a lot of cells. I just built a new .308 hunting rifle and before that I was using a Pipe rifle built into a sniper rifle (pretty good one). I also built a .38 sniper pipe rifle just to conserve ammo for light targets. I don't think of myself as a sniper character, but in the beginning when I'm particularly weak, it's nice to be able to think the herd before getting closer.