I am thinking how Bethesda will handle the caravans that you send between settlements. Currently I am playing Black Flag and like how the Fleet Trading system is set up for commerce within the game. Will you have to fight off caravan attacks within the minigame? Or take care of the route personally prior to sending out your caravan?
I would also like the monetary system to be more difficult. I have seen so few games with a money system that is well thought out. Most games after I am 60% through the game I have more money than I could ever use.