I'm completely baffled right now.

I finished Beyond Boulder Dome and when I come out, everything seems fine, but I go into certain interiors and the game's loading screen turns red, the game's textures go bonkers and there are exclamation marks everywhere.

Now, if I remove my merged patch, everything seems fine, but I lose a whole bunch of items and even when it's on/off, NPCs don't talk. No lip sync, no words, no sound, nothing.

I have NO idea what this could be - I've been playing Bethesda games for over a decade so I've seen a lot - and this is by far the weirdest issue. I've tried enabling ArchiveInvalidation and disabling it, haven't tried other saves but doubt that's the issue... what gives? The only things I did today were re-download Shiloh's clean Pip-boy mod and I remember a thunderstorm (IRL) shutting down my computer several times. Could I have a malfunctioning part? I doubt that is it, because like I said, if I remove the merged patch everything _seems_ fine...

Any idea? I can make a video of it if need be, please help. Someone here has to know.

First post your load order. You can select an option in the NMM next to your load order. Then maybe someone can help you.

Someone said on the Steam forums that after exiting the Boulder Dome mod, the game just doesn't want to load the Mojave resources. Could be true?

FalloutNV.esm
DeadMoney.esm
HonestHearts.esm
OldWorldBlues.esm
LonesomeRoad.esm
GunRunnersArsenal.esm
CaravanPack.esm
IWR.esm
Caliber.esm
Stalker Weapons Pack.esm
CaliberXgunrunners.esm
CFWNV.esm
Military NV Backpacks.esm
AWorldOfPain(Preview).esm
More Perks.esm
More Perks for Dead Money.esm
More Perks for Honest Hearts.esm
More Perks for Old World Blues.esm
More Traits.esm
NVInteriors_Core.esm
NVInteriors_ComboEdition_AWOP.esm
Primary Needs HUD.esm
SomeguySeries.esm
Arwen_NV_Core.esm
MaskRevamp0.02.esm
Weapons.of.the.New.Millenia.esm
IWS-Core.esm
WMVM.esm
YUP - Base Game + All DLC.esm
domecity.esm
CFW-DLC.esp
DarNifiedUINV.esp
CASM.esp
IWR - Rebuilt.esp
Purge Cell Buffers.esp
The Mod Configuration Menu.esp
The Weapon Mod Menu.esp
HUD Extended.esp
GoodspringsSewer-1.22.esp
NewStripMapMarkers.esp
NewVegasBounties.esp
NewVegasBountiesII.esp
More Perks Update.esp
More Perks for Dead Money Update.esp
More Perks for Honest Hearts Update.esp
More Perks for Old World Blues Update.esp
More Traits Update.esp
NV_STTraitsandPerks - NVSE.esp
Desaturated Cateye.esp
Lighter books.esp
pipboy2500_edisleado.esp
PortableCampsite.esp
Sprint Mod.esp
ArmourRepairKits.esp
Improved Throwing1.esp
mac10.esp
KDS Wearable Backpacks.esp
Military NV Backpacks - BumBagUseSlot1.esp
QS_Blackwolf_NV_Backpackmod.esp
AWOPCaliberXAmmoPatch.esp
AWOPLowLootGeneral.esp
AWOPLowLootMWeapons.esp
AWOPLowLootSkillBooks.esp
AWOPDeadMoneyVendorPatch.esp
AWOPDeadMoney.esp
Stealing -1 Karma.esp
aaaJNFSniperZooming.esp
AWOPLowLootMWeaponsArmor.esp
dD - Enhanced Blood Main NV.esp
dD-Reduced Ragdoll Force.esp
Faster Terminals.esp
NoQuestItems.esp
Honest Hearts Weight Check.esp
Zion Exit.esp
Fellout.esp
BetterGamePerformanceV4.esp
Shorter Chem Wear-off Effects.esp
Vurt's WFO.esp
ServiceRifleReflexSight.esp
OverTheShoulder.esp
XP_Sound.esp
Survivalist'sRifleFix.esp
More Mentats.esp
SITD - BoS at Nellis.esp
LFox Sink Bug Fixes.esp
MaskRevampLonesomeRoad0.02.esp
Water _Tower_Hideout_Reworked_v101.esp
The Free Man.esp
Zan_AutoPurge_SmartAgro_NV.esp
afvecw.esp
357retex.esp
Weapons.of.the.New.Millenia.Honest.Hearts.Grunt.Patch.esp
Weapons.of.the.New.Millenia.Store.esp
Weapons.of.the.New.Millenia.Leveled.Lists.esp
Weapons.of.the.New.Millenia.CaliberX.Patch.esp
GRA WRP Compatibility Patch.esp
implants.esp
WeaponModsixpanded.esp
WMX-AWOP-Overhaul.esp
WMX-ModernWeapons.esp
WMX-AWOP.esp
WMX-DeadMoney.esp
AG Supplementary Uniques-GRA.esp
WMX-HonestHearts.esp
WMX-OldWorldBlues.esp
WMX-LonesomeRoad.esp
WMX-GunRunnersArsenal.esp
WMX-MW-GRA.esp
WMX-ArenovalisTextures.esp
WMX-PreOrderPackCaravan.esp
WMX-AWOP Patch.esp
IWS-Core-Guards.esp
IWS-Core-Patrols.esp
IWS-Core-Civilians.esp
IWS-DM.esp
IWS-HH.esp
IWS-OWB.esp
IWS-LR.esp
YUP - NPC Fixes (Base Game + All DLC).esp
Leather Trench Coat NV v1.0.esp
JRougeRangerCoats4Loot.esp
Face Mask.esp
Realistic_Repair_NV.esp
TheInheritance.esp
Freeside Open Patch.esp
Hitman.esp
Russell.esp
Express Delivery.esp
SWP40Pistols.esp
SWP40 Patch 01.esp
ZLArmaments.esp
YKVendingRecipes.esp
AG Supplementary Uniques-AllInOne.esp
MaresLeg.esp
FO3ExperienceupSoundForFNV.esp
psychoelfs anti anti cheat.esp
Arwen_NV_Realism_Core.esp
Arwen_NV_Med-Tec.esp
WMX-Arwen_NV_Realism.esp
BetterRepairKits2b.esp
Expensive5.esp
BinglesMonsterToughenerCustom.esp
removechallengeperks.esp
Colored Piplight - White.esp
Piplight Brightness - 300%.esp
FO3WeaponsRestoration.esp
WeaponModsixpanded_FO3WeaponsRestoration.esp

Total active plugins: 147
Total plugins: 149

PS: Don't let the number of plugins fool you - the game has been perfect up until now (aside from minor issues weeks ago) so I don't think that's it. I deactivated my merged patch, too, and NPCs still don't talk, either way.

Here's a video of the problem. I know it's a bit long but please, watch.

Video here.

https://www.youtube.com/watch?v=w0kRbpwYLU0&feature=youtu.be