Guess i will start.
For me one of my biggest moments was in Final Fantasy 7. When that game came out i was hooked!! and i developed a huge crush on Aeris, i thought she was one of the most beautiful and adorable characters of all time, well i didnt have internet at the time so there was no way to know ahead of time what horrible event was coming. Anyway that moment came where Sephiroth killed her and for the first time ever in my gaming experience i actually cried, that scene impacted me so hard it upset me for days. So for the remainder of the game i was determined to get strong and get revenge on Sephiroth, then my moment came again when i finally faced him and cheered when i beat him and avenged Aeris.
Well thats one of my most memorable game moments, im anxious to see what you guys have to share.