I've added LAME to my install, in which I'm already am using Supreme Magicka. I load LAME before SM as I'd like to keep SM's settings overall but add new spells etc. from LAME. It seems to work just fine generally - haven't noticed any difference in spell costs etc. With one exception: suddenly the Minor Dispel spell doesn't dispel what it did before. Maximizing a spell with my current skill (60 on Self) doesn't remove them either. I've looked in TES4Edit but checking Minor Dispel it is Supreme Magicka that overrides other settings as it should. So it must be something else I should be looking for, but I'm not sure what? :unsure:
It's quite annoying as my char relies a lot on buff spells etc. and is used to be able to "turn them off".
EDIT: Same with the Dispel Magic Effect. It's also set by Supreme Magicka according to TES4Edit.