http://www.newvegasnexus.com/downloads/file.php?id=34868 let's you force SSAO on but it's artifactastic (for me at least) and it'll half your FPS if your not running quadcore/multi card setup, awesome for screenshots, wonky for actual gameplay. Looks nice but it's just not worth it unless you've got FPS leaking out your ears. The same can be said for virtually all of these "shader improvements" with the possible exception of http://www.newvegasnexus.com/downloads/file.php?id=35589.
Using a DOF mod (there are a bunch of them with differing levels of fuzz) will give you a fairly flawless (if highly subjective) improvement with a comparatively small performance hit. Really though, if you want more wow for no performance hit then just use http://lh6.ggpht.com/_z1odMghQc7A/TNL_mlLptkI/AAAAAAAAAG0/0WDs99pKNmM/s1152/ScreenShot26.jpg. Does more to improve the game than any of these half assed shaders.