Morrowind runs pretty well for me through Wine when I choose to boot Ubuntu, so I imagine if you have Wine or one of its variants on Mac it should run decently.
You won't be able to use MWSE mods (at least, I don't think) and probably not MGE (though another user has reported being able to get that working, I'm still not having any luck :brokencomputer: ), but anything else should be usable.
Good luck!