Fire Ants, annoying as hell. Specially if your low level doing those quest.

I hate Giant Radscorps more than anything else in the game. Not Albinos, just the regular old Giant Radscorps. I've been playing this game from the beginning and have hated them since long before BS came out.

no question the most aggravating enemy is Roy freakin Phillips.....I'm on my second play through and I still cant decide what to do with him since I always play a pristine karma character and dont allow myself to take any bad karma hits.....but I think this time Roy's gonna get his......

radscorpions
those little pricks can hear you sneaking from a mile away
i see the danger symbol flashing while im trying to sneak
i look off way into the distance and see a giant radscorpion charging at me from a mile away

and with no ears.....thats pretty damn amazing

gotta be the boatfly. I tend to just use a nuka-granade for two reasons: 1 - you cant miss 2 - its very satisfying using such a volent explosion on a pittiful little but thing like that lol

Bloatflies for avoiding all attacks apart from dogmeats.

Usually when i fight raiders, im fine, but when they are litterelly moving the ENTIRE fight, it annoys the [censored] out of me.

they miss you 75% of the time, and then you can run away, i really wish there were more than one aerial enemy.

my first playthrough i was getting slaughtered by a group of mirelurks over and over, thats an enemy.

Those Chinese Inferno Units and Chinese Launchers from O:A

there s a talon company hideout right around the corner from the library.

http://images2.wikia.nocookie.net/__cb20100511003123/fallout/images/thumb/a/a5/Royphillips.PNG/250px-Royphillips.PNG, because he's the only one I truly loathe the personality of.

I absolutely despise centaur's. With that damn waddle they do back, and forth when they move. Makes it difficult to hit them. Plus that radioactive crap they spew at you. Not to mention they were beatin with the worlds worst ugly stick lol :gun:

They actually take standard damage, it just seems like they don't because they have 1500HP and no real weak spots (they do take a little extra when shot in the tail).

My most annoying enemy used to be Bloatflies, since they're not worth bothering with and show up pretty much everywhere. I have since modded the Animal Friend perk to include them, which eliminated the problem. I wanted to use the Entomologist perk for that, but AF is set up significantly differently from the other perks and it would have been a pain reworking Entomologist to suit.

These days, my most annoying enemy would probably be Feral Ghoul Reavers, since they are by far the most common of the 'bullet sink' enemies and on top of that often get a surprise attack in before you can react to their presence. It doesn't help that there are at least three locations necessary to pass through for the MQ that are infested with Ghouls, which at high levels are almost all either Reavers or Glowing ones.

Which enemy annoys me most? I really don't know, I would say bloatflys, but all you have to do is weave back and forth and punch or slash it. Albinos/Giant Radscorpians you just have to circle and blast their tail. Reavers paralyzing palm...Overlords, shoot their weapons...Deathclaws, sneak crit their legs, then go for the head....Raiders die no problem...Yougi bears die easy...mole rats get bashed in the head....Dogmeat eats dogs...Kill aliens with their own weapons...Mirelurks use the Lincoln's Repeater and let them come to you, or use a shotgun. Either way uses less ammo then the old flamer trick.

I love all the enemies...

The enclave and sentry bots. <_<

Deathclaws are super hard or super easy to kill, depending on your weapons and level. Giant radscorpions are a pain cause they can tank it.

I found that Mirelurks can be killed reasonably quickly if you shoot to tear off their limbs. Just don't try shooting them in the body, is all. Damn tough armor there. The stupid hillbillies tend to die easily from the Shady Sands Shuffle if you can get close enough - at least, the three least powerful ones do, I haven't tried it on the big ugly bastards with the one lumpy arm. I tend to reserve my NukaGrenades for two things - bulletsink monsters and large groups of enemies. Or if someone/thing has been doing enough damage to me to seriously piss me off (enemies with rocket launchers, for example).

I have to say that bloatflies are the most annoying. And those damn hillbillies.

The other key place to kill mirelurks is with a shotgun blast to the face at close range. They may look like all shell, but in VATS, if you get them when they rear back and expose their underside, you'll see that a shot to the face does the most damage. I carry either a .44 magnum or a combat shotgun for the express purpose of blowing away mirelurks.

As a bonus, the combat shotgun does wonderful things to the heads of ghoul reavers.

Albino Radscorpians! Two of them came out of nowhere and attacked us. There were four of us but it wasn't enough -- Charon was killed. R.I.P, good friend.

Cliff Ra... Wait, wrong game!

The Point Lookout enemies that do 35 extra damage with Repeater Rifles and Double-Barrel Shotguns. Wepons designed in the 19th century shouldn't be able to take down someone in T51-B Power Armour.

If I have a companion: Super Mutant Behemoths, since I can't launch a Mini-nuke without incinerating my own guy.
If I'm alone: Mirelurk Hunters. Devastating and nearly indestructible.

exactly and at high levels you run into multiple albino scorpions, what a hassle. if you have companions you have to waste on em because otherwise they will kill your companion. when i'm romaing around alone i try to avoid, its a waste of ammo, or i'll g5et them to follow me maybe staying on rocks or something until something else like a bear or deathclaw fight it, the bear loses but at least it takes a bit a health down, deathclaws don't last long either but they do take a good bit of its health down.

Albino Radscorpions. Deathclaw I can handle easily. One headshot and they're down. Often from out of their perception range. Raiders, Enclave, Outcasts, they're the same way. One single headshot from out of their perception range(And sometimes even my own!) and they're down. Behemoths are incredibly easy with a stealth field active, spawn the brute and find a nice, high place he can't reach. Then just troll him with a BB rifle for ultimate lulz. Animal Friend renders the other two species of radscorp quite unhostile. The Albino ones, however...blarg.

i think your doing what all great leaders have done. tactically dealing with your enemies. i can easily kill an overlord with a stealth boy and a grenade in his pocket. a reaver... i have no idea how to deal with those things, and they dont die in a head shot. they dont die with a missile to the head.