I enjoyed my vanilla playthrough and would like to go for a 2nd run now, but with some nice mods.
The problem is there are so many of them...
Please tell me some recommendations and which good mods are compatible with each other. Here's some points I want to have in the mods, please help me choose

- Should be a big overhaul
- Realistic, not hardcoe realism, but no uber 1337 guns and armours that make you invincible
- New, nice graphics
- Loads of new stuff integrated
- vanilla Stuff improved
- some new factions would also be nice
etc. etc.
There's actually nothing I wouldn't want to have, except for uber 1337 stuff that makes you invincible and [censored]. I want to have a content rich, good looking, smooth and challenging game

Thanks for any help