This is spot on.
The three biggest issues with their concept are the no saving, no fast travel and the companion change.
Saving - Too many issues with the game to pull this off. Not talking about just crashes (like some people seem to think) but just bugs and other badly designed game aspects. Didn't know a certain NPC would turn hostile because you entered his cave with a certain power armor mod on your helmet? Well, now you will really suffer for Bethesda not fixing the brawl bug that's been a problem since skyrim. Die because your knee touched a car bumper as you ran past? Too bad, go back hours and replay your game. Make a permanent bad choice because of the crappy dialogue preview? Live with it or go back hours and replay. A NPC ran into the middle of a gun fight with a switchblade and got shot and your whole settlement is now enemies with you? Too bad, go back hours and replay to fix it. I could go on, I've played through the game five times now and probably have actually died half a dozen times total and mostly in the first play or by screwing around. However I've had saves help me fix countless bugs and get past lazy design decisions probably more than two dozen times. This isn't the type of game you have to save on before a big fight/encounter - it's the type of game you have to save afterward so you don't have to go back and re-clear an area or rebuild a settlement.
Fast Travel - I'm not much for fast travel, BUT poor design decisions can make it a necessity for some people. Combined with stuff respawning slower and you are creating a boring game for someone to have to walk back and forth across half the map for fetch quests. Also the whole settlement attacks (still have to see if they pull this off with a fix) is horrible as is. All the way down in the bottom of the map and settlement at the top with 500 defense gets attacked? Start walking - oh, and if you don't go, they will get destroyed and if you show up they are fine and the huge defense destroys all enemies. Settlement attacks are a huge waste of time in the game and were very lazily designed. Combine this with no saving and have fun with the walking simulator, especially when you have to repeat it because of going back to fix something.
AI/Companions - Again, lazily designed. Companion AI (all NPC AI in general) is horrible. I don't travel with companions, the couple of times I've tried I end up sending them away after one fight (even dogmeat). They svck up stimpaks ten times faster than I do already. Plus - Taking aim with a sniper rifle? Let me step in front of you. Trying to get through a doorway? Let me stand in front of you. Etc. Having a companion with you makes the game harder, not easier.
With the design problems of the game, these concepts, as amazing as they are, just won't work well. Fortunately I'm on PC and like many issues with the game that don't get fixed, mods will fix it. I feel for console players however.