I, of course, re-rolled and decided that choosing 1 profession was the best option; keeps things interesting, since I can actually find something of value. Ultimately, for a rping standpoint, I chose Smithing -- I play in all Elven gear, because honestly, what elf wouldn't. Aside that is: from my cool mask I found off a lich, which serves no real benefit as it doesn't have any stats that are good for me, but looks cool as hell. Lydia has the other one, and together, we scare the snot out of people -- and that is a scary last face to see before I cleave your head in.
I do use lockpicking, but assigned no perks too it; saw no point really since lockpicks are so common.
Now, my experience has been 100% better. I play on expert difficulty and I find the game is actually quite challenging at times, especially when it comes down to boss fights. Had a few memorable ones -- had a deathlord, scourge and some other skeleton at the end of one and man, that battle, even with Lydia was hard and the disarming shout made things extra intersting.