There seems to be no nuke in F:NV.

I personaly am a little bit disappointed that there is no nuke that has a big impact on the story like in F1 and F2.

How do you feel about that? Do you think that there will be one in the DLC?

Big nuke or mini nuke? I never really used the mini nuke in fallout 3 so i'm not really missing it. But it would by fun to have though

Keep in mind that this game takes place in the middle of a desert and is far away from large population areas, unlike the east and west coast settings of the other games. It seems unlikely that the area would have been nuked directly.

They give us the Archimedes laser to compensate, so its all good.

I didn't activate it... i'm too good for my own good

You need wild Wastelands perk (which imo is a waste) but you'll see a Nuke, can't set it off though.....

You mean "The Big One"? Yes i found it.

On "The Vault" it's said that Cesar's Legions droped a nuke on "Camp Searchlight". That means that they had at least one nuke so why can't there be more than one.

I think that in Nevada should be more military installations especially because there isn't as much civil population as in other regions.

Keep playing the main story and ask Mr. House questions. Vegas was targeted.