I have done all the DLC, Main Quest etc. I found the quest in Oasis to be the hardest choice I had to make in FO3. I chose to activate his heart so it would spread the seeds faster and farther. I realize that I was quite possibly dooming someone to live for centuries who didn't want to. Luckily he (Harold? Bob? HA) seemed cool with being "god" for these people.
As for "why" I felt that his influence on the wasteland would be irreplaceable even if it meant that he has to involuntarily suffer to do so. It wasn't an easy call to make.
I was so close to killing the poor bugger though. How did you finish the quest and why?
I too, thought long and hard about this when I first came across this quest. I chose as you did. Harold seemed okay with it when you explained it to him, and future benefits will be vast for thousands if not millions of people. I just wish we could have seen some sign of our choice, in the CW. Nothing big mind you, just.... something.
EDIT: My evil character cleared the place out, and it's now HIS Oasis in the desert.