The LAA enablers on tesnexus are reported to cause problems with OBSE. This one (suggested by showler in the other thread) is reported to work fine with OBSE: http://www.ntcore.com/4gb_patch.php
LAA stands for Large Address Aware.
Why enable LAA?
32 bit programs, including Oblivion, can normally only use 2 GB of address space.
If you set the LAA flag in a program, then the program can use more than 2 GB of address space if more is available. On 64 bit windows, 4 GBs of address space are available per process. On 32 bit windows, normally only 2 GBs of address space is available per process, though the /3GB switch can increase that to 3 GB. However, the /3 GB switch is generally not recommended.
A few programs may have trouble (ie crash) if they are given more than 2 GB of address space, but Oblivion is not one of those. However, Oblivion doesn't have much use for that much memory unless it's very heavily modded.
If you're specifically on 64 bit XP, then there is an extra complication:
Oblivions heap goes in to a sort of alternate mode after about 200 MB of heap allocations. This mode is REALLY slow on XP. You're likely to exceed this limit long before Oblivion could start benefiting from LAA. If you use OSR and have heap replacement enabled in the OSR ini file then that limit is increased to 450 MB by default, and can be increase further by ini file changes.
Here's the decision tree for heap memory considerations:
Is your Oblivion heavily modded?
___no: You might be fine.
___yes: Are you using windows XP?
______no: Is your Oblivion really REALLY heavily modded?
_________no: You might be fine.
_________yes: Are you using 64 bit windows?
____________no: You might have trouble.
____________yes: Consider using an LAA enabler.
______yes: Use OSR w/ heap replacement enabled. Is your Oblivion really REALLY heavily modded?
_________no: You might be fine.
_________yes: Are you using 64 bit windows?
____________no: You might have trouble.
____________yes: Consider using an LAA enabler. If you do so, try changing increasing Heap\iHeapSize from 450 to (making up a number) 700 in the OSR ini file. The change is unnecessary (but doesn't hurt) for some settings of iHeapAlgorithm.
There may also be some issues with non-heap stuff that uses address space, but I don't know anything about that.
I personally do not use an LAA enabler for Oblivion. I don't use enough mods to benefit from it.