I did it once on my first playthrough, I used Sneak and duel-daggers. Basically I was ontop of a Mountain in The Pale when I saw a Blood Dragon resting on a word wall. So I scaled down the mountain (she'll be scaling down the mountain when she comes ) very very slowly and to my suprise, I was standing right behind the Dragon. I wasted no time in flurrying my blades and killing the Dragon. I was in awe, I though it both amazing and utterly ridiculous at the same time. I had a couple of those moments during my first playthrough..
What about you?