I don't know if this is a glitch caused by a mod so I'm posting it here instead of tech support. I have rested for weeks and used the detoxify function on My First Infirmary but it won't go away. I've tried taking more of Orange Mentats, and the after effect still persists endlessly. Unless someone has any ideas, it seems my character is stuck with a permanently crippled Perception attribute.

post your load order

Fallout3.esm
Anchorage.esm
ThePitt.esm
BrokenSteel.esm
PointLookout.esm
Zeta.esm
CALIBR.esm
Project Beauty.esm
CFWRv4.esm
Mart's Mutant Mod.esm
fatman_t default.esp
Slower Levels (300).esp
Project Beauty- Broken Steel.esp
Project Beauty- Point Lookout.esp
RaiderMercenaryExpanded.esp
CALIBRxMerchant.esp
Overhead3PCamera.esp
Wasteland Weather Overhaul .9 (no interiors).esp
Burnification.esp
EVE.esp
Mart's Mutant Mod.esp
Mart's Mutant Mod - DLC Anchorage.esp
Mart's Mutant Mod - DLC The Pitt.esp
Mart's Mutant Mod - DLC Broken Steel.esp
Mart's Mutant Mod - DLC Point Lookout.esp
Mart's Mutant Mod - DLC Zeta.esp
Mart's Mutant Mod - No Corpse Flies.esp
Mart's Mutant Mod - No DLC Increased Spawns.esp
Mart's Mutant Mod - No Ghoul Raise.esp
Mart's Mutant Mod - Hunting & Looting.esp
Mart's Mutant Mod - Natural Selection.esp
Mart's Mutant Mod - Tougher Traders.esp
Mart's Mutant Mod - Project Beauty.esp
NightvisionGoggles(Powered).esp
KillableKidsNormalHealth.esp
Owned!.esp
dD-Less Blood Time.esp
dD-More Gore.esp
dD-More Gore-PointLookout.esp
dD-More Gore-BrokenSteel.esp
dD-More Gore-The Pitt.esp
dD-More Gore-Zeta.esp
dD-Reduced Ragdoll Force.esp
dD-Reduced Dismember Force.esp
ShellRain.esp
ZumbsDarkerSunglasses.esp
reduced karma loss for Stealing.esp
Accurate Assault Rifles 1.2.esp
Supersledge Knockdown.esp
RadiationSuits.esp
OutcastRewards.esp
Mesmetron Works on Everyone.esp
Night Stalker.esp
Moriartys_Key_Restored.esp
Moriartys_Strongbox.esp
Psychoelfs - No more wasteland robots.esp
MrSlackPants-Radiation.esp
Neunen Fireaxe.esp
BurgerBoyCompound.esp
RaiderMercenaryExpanded[MMM].esp
ExtreemeLongDeathCamera.esp
Energy skill Gatling Laser.esp
Deadly Mines.esp
Cannibal Perk Improvements.esp
Dread Dogmeat.esp
Pulse Grenade (vanilla sound).esp
SuperSledge.esp
EssentialNoMore.esp
FastTravelFromParadiseFalls.esp
Badass Super Mutants BIG GUNS Mod.esp
EnclaveCommander-OA.esp
Explosive Entry.esp
Ghouls Cohabitate.esp
FollowersHireContinued-KarmaCheck-NoCharismaCheck-NoCountCheck.esp
MotorCycleRemake.esp
CFWRloadlastEVE.esp
Bashed Patch, 0.esp

Total active plugins: 77
Total plugins: 78

Have you changed your load order recently? If you are under the effect of a piece of clothing or ingestible, and save, and then add or remove a mod that changes the stats of that effect, your stats will not return to normal when the effect wears off. For example, if unmodded orange mentats give a +5 perception boost, you take them, and save before they wear off, then add a mod that makes the perception boost +7, your perception will be lowered by 7 when the effect wears off, meaning it will always be 2 lower than what it should be. It can be fixed though.

If that is the problem, you can type "player.modav perception 2" in the console and it will go back to normal for all intents and purposes, except that if you type "player.getavinfo perception", the "temp" value will be -2, and the "permanent" value will be 2, rather than both being zero (i forget which heading those two values are placed under, modifiers or something, but they're easy to spot). You can also reverse it, I think, by doing the opposite of what caused the problem - take orange mentats, save, remove (or re-add) the offending mod, then things should go back to normal once the effect wears off, and you can save and put your load order back to normal (and getavinfo will return the right stats).