I installed the game. Installed the mods, and pressed play.
=)
Almost. Installed the game, the mods, NVSE and the 4gb loader for it, start Wrye Flash, run BOSS, create bashed patch and correct wrongly imported items with FNVEdit.
Sometimes a reinstall helps too. I had a freeze on exit problem recently, just reinstalling the game made that go away, even with the same mods installed. Should learn to make BAINs of the mods i use, would make the reinstall procedure much less of a pain