I dont really agree, I dont feel any need to get damage increasing perks, properly modded guns with drugs we have access to without needing to get any perks turn any fight into joke, including boss battles, When you have properly modded weapons, drugs arent even needed most of time. Hell the minuteman encounter with 'queen' ended very quickly only by using gear I found early in game(fat man and missile launchers, we have MUCH to early access to those weapons) and time slowing drugs, it literally ended in few seconds