No, they probably wont. Perks probably wont cover luck, or the difference between personality and speechcraft, or the separate variable of strength/agility opposed to weapon skill.
"Probably won't" and bam, that's where you lost. If you said probably won't there, then you can say Dragon fights probably won't be cool, or that AI probably won't be good. Probably isn't valid because I could say you probably won't be right. Luck was dumb anyways, seriously? All it did in ES was raise all your skills just a little. Personality didn't matter, other than increasing speech and merc, but even then, I could just level speech and raise someones disposition, so personality wouldn't even matter there. Ok, no strength or agility, strength affected melee damage, encumbrance, and fatigue, right? and agility covered fatigue I think, i forget but whatever. Instead of having Str increase all that, you could just increase them directly (when you level up, increase health, then pick a higher dmg perk, then next time you level, pick fatigue) it's rather simple, it cuts out the middle man.