I've said this before in threads like these, but there seems to be a POV difference between some players.
Some players play
as the character, the character is themselves in a sense, so it makes sense it would be awkward for them to play a character of opposing gender.
People like me however play
with the character. I don't think i am the character, i'm an outsider affecting how the game proceeds, a "director" if you will. As such i have no problem playing a character of opposing gender. (Also the reason why arguments involving the i-word are lost to me
)
Personally i find playing as myself more awkaward, mostly because of what i would do isn't usually an option, it's easier in those situations to play with a character that is very unlike me.