After playing Fallout New Vegas, I've realized their was a lot of places with big spaces that went to waste. Like for example the Lucky 38 had a lots of space but it all went to space because of Mr. House didn't allow anyone to go into the Casino accept the Courier. Imagine how awesome it would be if there were tons of people, lots of people in the cocktail lounge, lots of rooms. I'm happy that luxury casino with the masked people didn't go to waste, that was enjoyable. Another place that had big space that went to waste was Freeside, basically half of Freeside had boarded up. There was tons of places that could've been restaurants, motels, drug stores, jail, small times casinos other than just one, food stores, town hall, and heck even a school.
I hope in Fallout 4 all the big places have some purpose and won't just be boarded up like in Freeside.