It will most likely conflict with FWE's balance and vision...
with the mod its self it will conflict because FWE modifies some of the original perks
If you really want it you could get UPP without the vanilla perk changes and forget the balance issues with FWE
or if you want the vanilla perk changes set UPP to load AFTER FWE
They're just perks anyway..nothing serious should happen if they conflict. The mod loading last will just over ride the conflicting perks with the other mod.