After you create and save a mod as I can charge it to resume where you left off earlier? I can not help me rpovato in every way but both the Gecko crashes me!

I'm not sure I understand but if you mean 'Can I resume editing a mod that has previously been created and saved?' the answer is yes. If the GECK crashes before you save then anything new is lost obviously but the original save is unaffected.

how can i open the mod who are in my computer desktop??

The mod needs to be installed to Fallout3\Data as if you were to play it otherwise the GECK can't find it.

And you need to click that button that says 'Set as Active Plugin' when you load it.