» Sat Feb 19, 2011 6:56 am
Depends on the mod. There are a couple which require a new game and a couple which require a certain quest or DLC to be completed first. Most quest mods have the info in their Readme or description if they need to be played in that way. I'm doing a game now consisting solely of quest mods with no vanilla quests completed at all so I installed all of my mods before beginning my game.