-Display icons on potions in our inventory - so we don't have to search through a bunch of unmarked bottles by going over them with our cursor.
-An option to hide UI on screenshots so we don't have to turn crosshair off and such when going for a nice landscape SS for our desktop or whatever. (And a hide when out of combat toggle too)
-Ability to poison a number of arrows per bottle of poison(and enchant a number of them per soulgem). Poison should also last longer on melee weapons, to be fair.
-Alchemy apparatus that we don't need to carry in our inventory - in places like mages guild that you activate and they just open up your alchemy screen, similar to enchant altars.
-Allow us to stack potions with the same effect, just make it average the strength of all them or something - as if we mix them all and re-bottle them I guess. Having 10+ potions of the same effect that are all just slightly different is annoying.
What minor annoyances would you like to see dealt with in Skyrim?