I've had certain problems with quests where certain scripts in the quests don't run or conditions aren't met when they have been. The quests so far are:

- MG01 Skingrad Recommendation (Erthor won't leave the cave.)
- Mages guild quests where you need to go to the Bruma guild hall
- Main quests.

It's getting really frustrating and I don't know why it's happening.

Do you have the UOP installed? The vanilla game does have a lot of bugs in it...

post your Load Order, and, if you have a quest mod called Five Blind Mice, be sure to get http://www.tesnexus.com/downloads/file.php?id=24580 to fix that possible problem.

lol, why did I mention that quest mod? because it is problematic, especially without the fix. It ruined mage guild quests for me, along with several others. :hehe:

Post Your Load Order - http://sites.google.com/site/oblivionpoinfo/troubleshooting/postlo

Oblivion.esmDremoraCompanion.esmCobl Main.esmCyrodiilUpgradeResourcePack.esmFort_Cooper.esmCM Partners.esmToaster Says Share v3.esmKvatch Rebuilt.esmEnhanced Daedric Invasion.esmSB IC Palace Tower Light Mod v1.1 - Modified Version.espUnofficial Oblivion Patch.espUOP Vampire Aging & Face Fix.espOblivion Citadel Door Fix.espDLCShiveringIsles.espUnofficial Shivering Isles Patch.espNatural_Weather_by_Max_Tael.espNatural_Habitat_by_Max_Tael.espNatural_Water_by_Max_Tael.espM.O.E. - Undermined Leveled Gameplay - Creature Edition.espM.O.E. - Undermined Leveled Gameplay - Item Edition.espPortable Campsite.espRAEVWD Cities.espRAEVWD Imperial City.espReznod_Mannequin.espMaleBodyReplacerV4.espM.O.E. - New Staffs, Blight and Ashstorms.espM.O.E. - Unlocked Palace Guard Armour.espM.O.E. - Unlocked Dremora Armour and Robes.espRTFemaleReplacerV12.espSoT_Rise of Sheogorath.espkikaiAS-SheogorathRT-sep.espCobl Glue.espCobl Si.espCobl Tweaks.espFort_Cooper.espM.O.E. - Tools of Kagrenac - The Secret of White Gold Tower.espM.O.E. - The Black Sacrament - Night Mother's Ritual.espSoT_TheOrderofNibenay.espTheElderCouncil.espKnights.espTOTF.espRTT.espElsweyrAnequina.esproad+bridges.espNatural_Vegetation_by_Max_Tael.espM.O.E. - Bone Names and Priced Skull.espM.O.E. - Icons for Mythic Dawn Armour - Fix.espM.O.E. - Lycanthropy and Lichcraft.espM.O.E. - Realistic Prices, Realistic Weights, No Quest Items.espBorderless_Cyrodiil-3578.espM.O.E. - Vampire Clan Raelu.espM.O.E. - Ethereal State Spell.espM.O.E. - Lock Spells.espM.O.E. - Mythic Dawn Powers.espM.O.E. - Teleportation Magic and Icarian Flight.espMadgod Powers.espTeachSpell.espSupremeMagicka.espSM_EnchantStaff.espSM_VanillaSpells.espSM_UnlockSpells.espSM_Scrolls.espSM_SigilStone.espbgMagicEV_Conjuration_for_Supreme_Magicka.espRenGuardOverhaul.espactors_in_charge.espActorsInMadness.espM.O.E. - Playable Dremora and Custom Race Fix.espCM Partners.espAsharasCMPartners.espDremoraCompanion.espbgBalancingEVCore.espbgMagicEV.espbgMagicItemSigil.espbgMagicEVStartspells.espbgBalancingEVOptionalFangs.espbgBalancingEVOptionalMoreEyes.espbgBalancingEVLAMEAddition.espbgBalancingEVLAMEGlue.espbgMagicShaderLifeDetect.espbgMagicLightningbolt.espReal Lava 1.3.espNRB4 Standard Road Record.espBashed Patch, 0.esplumi_enchantments.espwalklikesheo.espAsharasCMBeasts.espCompanionMaster.espSummersetLandscapes.espSummerset.espCastle_Wolfspike.espWayshrines.espXilselem.espSide's Sailing Ships.espCommunalGraves&FreshTombs1.5.espElsweyrAnequinaFemaleBody.espSpells.espNecromancy.espEnhanced Daedric Invasion.espAmajor7 Imperial Furniture.espBeautiful People.espImpeREAL City Unique Districts - All the Districts Visible From Cyrodiil.espDACog-Rein.espKvatch Rebuilt.espLetThePeopleDrink-Cobl.espMannimarcoComplete.espImpeREAL City Unique Districts - All the Districts - Let The People Drink Compatible Version - Merged.espDBSRebuiltComplete.espPortableAltars.espFearsomeMagicka.espEmpire.espEnhanced Grabbing.espIWR-Windows.espIWR-Lights.espIWR-Shutters.espMage Equipment.esp

I have UOP installed and don't have Five Blind Mice installed.

can't help with the 2nd and 3rd ones, but I had a problem with Erthor years ago. Is it that,

Just move the quest on with the console.
Never had it since and wasn't using UOP then (and I do that quest EVERY game)

EDIT: Also, you've, like, 30 mods AFTER your bashed patch. Update http://code.google.com/p/better-oblivion-sorting-software/updates/list

That's the problem I'm having but I'm also having it with other quests as well. I have UOP installed.

Fixing your load order should definitely help. It is quite disorganized.

Load Ordering - http://sites.google.com/site/oblivionpoinfo/finishinstall/loadorder <-- Grab BOSS, and use the template on this page to place unknowns in appropriate locations.
Popular Outdated Mods - http://sites.google.com/site/oblivionpoinfo/stabilization/outdatedmods <-- about IWR...

You cannot run Beautiful People with the Race Balancing Project mod. Choose one or the other. In the future, please post your load order through Wrye Bash. That way, we can see version numbers and the various plugin states that Bash supports. Right-click on the File tab, and choose "List mods."