King Lysander was a Septim so his son would have a legitimate claim on the the throne, if his son is still alive, not having played the bleeping game I wouldn't know.
His son, Gothryd, is the King of Daggerfall during, well, Daggerfall. I think he's still alive by Oblivion, due to this excerpt from the 3rd Edition of the Pocket Guide to the Empire:
"King Gothryd and Queen Aubk-i's own marriage twenty years before had cemented relations and formed the basis of the peace between Daggerfall and Sentinel, which continues to this day."Of course, it could just be referring to the peace relations that "continue to this day", but I doubt they're dead by now.