So, I know there is a patch coming out soon to fix all these problems, but here's an interesting one: Each time I've had to load the wasteland, it has gotten longer and longer. How do I know? Other than the obvious time factor, I started with only 1 background picture and it was done loading. Now, I am up to 3 background picture rotations, which takes a full minute, or more to load. Why is it doing this!?

Also, my game has frooze up numerous times (As well as it just freezing up for 5 seconds, then be able to play for 2 before It freezes up again).

I too have noticed that my game is getting longer to load. I have decided to stop playing until the patch comes out and hopefully fix this problem. Anywho....I just picked up AC:brotherhood and it is awesome...Hurry up Bethesduh so i can get beck to the wasteland.

I agree when my game glitched I stopped and restarted it and it glitched faster. I got annoyed and gave up but will continue the game hopefully.

I would try installing the game to the HDD if you haven't already, then clearing cache upon each load of the game (LB, RB, and X - all held simultaneously while you load the game, until the Bethesda logo appears).
I'm pretty sure there is a bad memory leak in there. I do this each time, and also quit out and reload if I am playing for more than 2 hours at a time. Seems to help. Also, if you want to be extra safe, turn off Autsave and back up your save files every once in a while to a USB memory stick. That's what I do, and I'm guessing thats about as safe as you can play it, other than avoiding all the various places people have mentioned are glitched.

I clear the cache when the load takes longer than normal. It always speeds it up for me. Having the game on the hard drive helps too.

I always clears cache on booting up and have not encountered any prolonged loading as a result.

Turn off the Xbox and turn it back on. Seriously.

Speeds it back up again.

It'll take less time than one loading screen if you've been playing for a while.

I get maybe 15 mins of play time before the game freezes and I have to reboot the 360.....The other day i felt lucky, I played an hour before it froze in the wastlands....yippeee, I played the game for a full hour...60 bucks for a game I get to maybe play 15-60 minutes without a glitch...